Brand Name(s): Celebrex, COX-2 Inhibitor
Generic Name:Celecoxib
Drug Class:Oral
Description:Celebrex (celecoxib) is a medication primarily used to manage pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. It belongs to the nonsteroidal anti-inflammatory drug class and is primarily used to relieve pain and reduce inflammation. Celebrex is known for its ability to reduce pain and inflammation, making it a reliable option for managing conditions such as osteoarthritis, rheumatoid arthritis, and acute pain. The medication's active ingredient is celecoxib, which works by inhibiting an enzyme called COX-2, which is responsible for producing the prostaglandins that are released by tissue cells during inflammation and pain. This mechanism of action makes Celebrex an effective treatment option for managing pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis, and acute pain.
Dosage Formulations:The typical starting dose for Celebrex is 10 mg, taken once or twice daily. The dosage may vary based on the condition being treated and response to the medication. Depending on the condition being treated, the dosage may be increased to 20 mg or decreased to 5 mg. It is important to follow your healthcare provider's instructions regarding dosage and duration of treatment.
Administration:This medication should be taken by mouth with or without food. It is usually prescribed with or without food as directed by your healthcare provider. It is important to take Celebrex at the same time(s) each day to maintain steady levels of the medication in your body. It is also important to swallow the capsules whole with a full glass of water. It is important to take Celebrex with food to minimize the risk of stomach upset.
Contraindications:If you have a known hypersensitivity to celecoxib or any of its ingredients, you should not use this medication.
Warnings/ Precautions:The dosage and administration may be contraindicated in patients with liver disease, severe heart disease, or uncontrolled hypertension. The presence of blood in the urine and/or in the stools can increase the risk of complications such as kidney stones. If you are allergic to celecoxib or any of its ingredients, you should not use this medication.
Food Warnings:Do not eat grapefruit or drink grapefruit juice while taking this medication. Grapefruit and grapefruit juice can interact with celecoxib and cause serious side effects. Additionally, patients with a history of liver problems should avoid taking celecoxib because of the risk of severe liver damage. Regular monitoring by a healthcare provider is necessary to assess any potential drug interactions.
Consultation:If you are taking any other medications or are taking other medications, it is important to inform your healthcare provider about all the products you use, including over-the-counter medicines, vitamins, and herbal supplements. This will help avoid possible interactions.
Missed Dose:If you miss a dose of Celebrex, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take 2 doses at once to make up for a missed dose.
Overdose:An overdose of Celebrex may cause severe side effects such as kidney or liver damage. It is important to seek medical attention right away if you experience any of the following signs of allergic reactions: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Overdose Precautions:If you are taking any medications, including over-the-counter drugs, it is important to inform your healthcare provider about all the products you use, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements. It is important to follow your healthcare provider's instructions regarding the dose and duration of treatment.
ReferencesPfizer Inc. said Monday it has closed 11 deals that it said were in the process of finalizing the acquisition of Warner Chilcott Corp. to settle a lawsuit alleging that it engaged in a "commercial fraud" by selling prescription drugs that were being used to treat cancer and other ailments.
The deal closed Thursday afternoon, when a court ruling was upheld in a lawsuit filed by Pfizer and other drug makers in New Jersey. It is the latest in a series of deals that have brought Pfizer and other drug makers to the attention of the public.
Pfizer has denied all wrongdoing and the Food and Drug Administration has never approved or authorized the sale of the drugs to treat cancer. The FDA has not issued a warning about the drugs that are now being sold, and no warnings have been issued.
The drug industry is fighting to get drugs off the market. Last month, the U. S. Food and Drug Administration issued a warning about the dangers of over-the-counter sales of prescription drugs. The FDA has also issued a similar warning about a drug called Bextra that could cause serious side effects.
The Pfizer settlement, which was announced as a $2.1 billion settlement by U. officials, includes sales of two of Pfizer's top-selling drugs, Vioxx and Celebrex, and an agreement with Warner-Chilcott and other drug makers that they will not sell or use the drugs.
In an interview on Tuesday, Pfizer spokesman Paul Gilmartin said that the company was not seeking compensation for the losses that were suffered by Warner-Chilcott and its co-promotion partner, Warner-Lambert.
"We are committed to bringing the drug industry to the attention of the public and as a result we are disappointed and disappointed in the settlement," Gilmartin said. "We are disappointed with the outcome of the settlement and we will continue to work with our partners in New Jersey and New York to reach out to our consumers and patients."
officials, includes sales of two of Pfizer's top-selling drugs, Vioxx and Celebrex, and an agreement with Warner-Lambert that they will not sell or use the drugs.
The deal closes on Tuesday afternoon after a long delay of Pfizer's planned settlement. The drug company said it will pay $2.1 billion to settle claims that it was selling a class of drugs that treat anemia, cancer and pain.
The settlement does not address the question of whether Pfizer will pay for the drugs and they are not covered by the settlement. The companies have agreed to settle claims that the drugs are unsafe, that they were not effective, and that they were not used for medical purposes.
Pfizer and Warner-Lambert said that the company's lawsuit is not related to any drugs that were withdrawn from the market. They said that the company has also paid for the $2.1 billion Pfizer settlement in excess of $3 billion.
Vioxx and Celebrex are both FDA-approved anti-inflammatory medicines for patients suffering from osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, respectively.
Pfizer and Warner-Lambert said that they would not sell or use Vioxx and that they would only sell Bextra. Both companies have agreed to pay for Vioxx.
In its news release, Pfizer said that the company would not disclose the $2.1 billion settlement that it is in the process of settling.
The company also said that it will pay for Warner-Lambert and that it is not certain whether the company will pay for the drugmaker.
The company said that the company will not pay for Vioxx and that it will not pay for Warner-Lambert and the other companies.
Pfizer said it will continue to work with its partners to make sure that the deal is successful and to ensure that Vioxx and Celebrex continue to be effective and safe. The company also said that it will continue to work with its partners to reach out to its consumers and patients to help them make better decisions about their health.
The Associated Press contributed to this report.Copyright © 2025 KPRC. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.Celecoxib, commonly known by its brand name Celebrex, is a nonsteroidal anti-inflammatory drug (NSAID) used to manage pain and reduce inflammation in conditions such as arthritis, pain with rheumatoid arthritis (RA), and osteoarthritis. It is primarily used on the treatment of migraines and chronic fatigue syndrome (CFS).
The global market for Celebrex drugs, including COX-2 inhibitors, was valued at USD 12.59 billion in 2023 and is expected to reach USD 13.61 billion by 2033, growing at a CAGR of 2.40% during the forecast period of 2024-2033[1][4].
About 18% of the global Celecoxib market is amorphous and consists of commercially available generics. Celecoxib is the most common product type, followed by aspirin and ibuprofen. Celecoxib is the primary source of revenue for the global Celebrex drugs market, with an estimated USD 12.59 billion in 2024. The Celebrex amorphous drug market was valued at USD 12.59 billion in 2023 and is expected to reach USD 13.61 billion by 2033, with a CAGR of 2.40% during the forecast period of 2024-2033[1][4].
Several factors are driving the growth of the Celecoxib market:
The rising incidence of gastrointestinal disorders, including gastrointestinal bleeding, is a major driver, as pain and inflammation associated with arthritis and other inflammatory conditions increase the demand for Celebrex drugs[4]. -Prevalence of Obesity-The increasing prevalence of obesity, including an increasing trend of overweight and obesity- are significant challenges for Celebrex market players. -Improved Healthcare Access and Quality of Life-The market is expected to grow at a CAGR of 2.50% from 2024 to 2030[4].
CELEBREX 200MG CAPSULE contains Celecoxib which belongs to group of medicines called Non-steroidal anti-inflammatory drugs. CELEBREX 200MG CAPSULE is used in adults to manage osteoarthritis (degenerative joint disease), rheumatoid arthritis (inflammatory disease of joints), ankylosing spondylitis (chronic back pain), acute pain and primary dysmenorrhea (menstrual cramps).
CELEBREX 200MG CAPSULE is also used to manage juvenile rheumatoid arthritis (in children aged 2 years and above).
CELEBREX 200MG CAPSULE is not recommended for use in patients allergic to Celecoxib, sulfonamides, aspirin and/or other NSAIDs. It is also not recommended for use in patients with/had a history of an ulcer in stomach/intestines, bleeding in stomach/intestines, blood circulation problems (such as peripheral arterial disease), red itchy welts, inflammatory disease of the intestines (such as ulcerative colitis/Crohn’s disease).
The medicine is also not indicted for use in patients suffering from lung problems (such as asthma), heart diseases (such as heart failure, recent heart attack, heart block), severe liver disease (such as advanced hepatic insufficiency) and/or kidney disease (such as advanced renal insufficiency).
Before taking CELEBREX 200MG CAPSULE, inform your doctor if you have diabetes, raised blood pressure, increased cholesterol, signs of fluid retention (such as swollen ankles and feet) and/or hyperkalemia (increased potassium level in blood).
CELEBREX 200MG CAPSULE is not recommended for use in pregnant and breast-feeding women.
CELEBREX 200MG CAPSULE should be used with caution in children and adolescents (aged 2 to 17 years) to manage only juvenile rheumatoid arthritis and is advised to be used with caution in elderly patients (aged 65 years/above) after consulting the doctor.
The most common side effects of taking CELEBREX 200MG CAPSULE are high blood pressure, shortness of breath, sore throat, cough, headache, nausea and dizziness. Consult your doctor if any of these symptoms worsen.
ReferencesZithromax Emin; El-Sawun. Jadad For. Ilan. Efarimaz. Ahmed. Abu-Saay. Das Saat-i-Azim. Das-Azim. Das-Iyaz. Din-Saaz. Din-Saaz-Ade. Das-Ada-Iyaz. Das-Awaay. Das-Ahab. Das-Bin. Das-Bin-Iyaz. Das-Bin-Bin. Das-Din-Ade. Das-Din-Ade-Din. Das-Din-Ada-Iyaz-Ade. Das-Din-Ada-Iyaz. Das-Din-Ada-Iyaz-Iyaz-Ade.
Stade de France Pharmacy